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The FraA adhesin and Ebp pili mediate Enterococcus faecalis adhesion under fluid flow

Enterococcus faecalis is a frequent cause of infective endocarditis and catheter-associated urinary tract infections (CAUTI). Successful colonization is challenged by blood and urine flow and relies on a strong and resilient bacterial attachment. Here, we identify molecular determinants that enable E. faecalis to maintain adhesion under flow, notably the flow-related adhesin (FraA), a previously…

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