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Satellite glial translatome reprograms to favor mitochondrial and vesicular signaling under pelvic pain conditions

Sensory satellite glial cells actively contribute to inflammatory and neuropathic pain, but their roles in pelvic pain remain unclear. This study examined how the active translating mRNAs in sensory SGCs change during pelvic pain symptoms using translating ribosome affinity purification followed by RNA sequencing (TRAP-seq) in a chronic pelvic pain (CPP) mouse model. Our data showed that SGCs…

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