Perinatal high-fat diet induces systemic inflammation via altered tight junction complex organization during development and decreases expression of intestinal satiety peptides in male offspring.
Objective Epidemiological evidence suggests that maternal obesity increases risk for offspring obesity and comorbidities, pointing to the significance of critical periods of development. Adverse metabolic effects of high fat (HF) diet consumption on the gut microbiome and inflammation have been well documented in obesity models. Emerging evidence demonstrates that the gut microbiome may play a…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
