ECMExplainer: a functional matrisome framework for decoding cellular stress states and aging trajectories
The extracellular matrix (ECM) is increasingly recognized as both a hallmark of aging and a durable record of the cellular stress states that shape age-related tissue dysfunction. Despite its apparent role in aging and disease, translating matrisome gene expression into interpretable biological meaning remains an unresolved challenge. Here we introduce ECMExplainer, a framework that uses 180…
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