A unified and practical taxonomy for false discovery rate control in omics research
Nature Biotechnology, Published online: 13 November 2026; doi:10.1038/s41587-026-03379-8 False discovery rate (FDR) control is central to omics research, yet the diverse procedures used rely on different assumptions. This Comment proposes a 2 × 2 matrix that helps sequencing-based and mass-spectrometry-based omics researchers choose the appropriate family of FDR procedures, or alternative methods…
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