Synaptotagmin 7 differentially regulates synaptic vesicle trafficking at tonic and phasic synapses
Synaptic vesicle (SV) release probability can differ across neuronal subtypes, but the molecular mechanisms establishing such differences remain incompletely understood. In the current study we demonstrate that Synaptotagmin 7 (SYT7), a calcium-sensor regulating SV trafficking, is enriched at Drosophila tonic Ib synapses compared with phasic Is synapses. Loss of SYT7 preferentially enhanced…
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