Cxcr2 is required for ductal outgrowth and shapes the stromal microenvironment in postnatal mammary gland development
Mammary gland development requires coordinated signaling between epithelial and stromal compartments. While CXC chemokine receptor 2 (CXCR2) is known to regulate inflammatory and tissue remodeling processes in disease, including breast cancer, its role in mammary gland morphogenesis is not well understood. Here, we examined postnatal mammary gland development in germline Cxcr2 knockout mice. Loss…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
