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AKAP-CaN-NFATc3 signaling drives persistent inhibitory long-term potentiation

GABAergic inhibitory synaptic plasticity has critical roles in neuronal function, synaptic plasticity, and cognition. Activity-dependent alterations in gene expression are essential for generating long-term changes in inhibitory postsynaptic strength, yet the signaling mechanisms that drive inhibitory postsynaptic plasticity are not well understood. During an important form of inhibitory…

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