A multi- tissue atlas of age-associated differential transcript usage in mouse reveals predominantly regulatory isoform switching across brain, liver, and adipose
Alternative splicing is increasingly recognized as dysregulated in the aging process across tissues and affects proteome and other regulatory changes which can be biomarkers of aging. In this study, we aimed to identify differential transcript usage (DTU) and isoforms switch accompanied with functional annotation and structural analysis in mouse brain, liver and adipose tissue during natural…
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