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A Glutamate-Neuropeptide Circuit Converts Transient Mate Contact into a Persistent Local Search State in Caenorhabditis elegans Males

Transient sensory encounters can trigger behavioral states that persist long after the initiating stimulus has disappeared, yet how neural circuits initiate and sustain these states remains poorly understood. Here, we show that brief contact with a suitable mate induces a persistent local search state in male Caenorhabditis elegans, characterized by increased reversals and spatially restricted…

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