Mechanism and subunit-dependence of disease-associated lurcher mutation in AMPA-type glutamate receptors
AMPA receptors are glutamate-activated neuroreceptors responsible for the majority of fast excitatory neurotransmission in vertebrate brains. Activity-dependent changes in their functional and trafficking properties underpin cognitive processes such as learning and memory formation. In the past 15 years, a number of mutations within AMPA receptor genes have been identified as disease-causing…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
