Lifestyle-mediated shifts in the gut microbiome and host genetics modulate gene expression in intestinal organoids
Industrialization-associated shifts in the gut microbiome have been linked to disease, but the mechanisms by which microbial communities influence host gene regulation remain poorly understood. We developed a live microbiome-colonic organoid (colonoid) co-culture system to investigate genotype-dependent host responses to gut microbial community variation. Colonoid 2D monolayers from healthy…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
