Genomes2Genes: A Progressive Cactus Gene Analysis Pipeline
Whole-genome alignments are fundamental resources in comparative genomics, because they place genes and their surrounding sequences in a shared evolutionary context. Progressive Cactus aligns large numbers of genomes without a reference genome and reconstructs ancestral sequences along the input phylogeny. However, its Hierarchical Alignment Format output has mainly been used for visualization,…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
