Deep CyTOF immune profiles of ex vivo granulomatous responses to Mycobacterium tuberculosis differ with European and African geographical origin
Genetic and environmental factors influence human immunity and modulate responses to infection. Accounting for immune heterogeneity across human populations is critical to the design of novel vaccines and host-directed interventions that would optimally benefit populations experiencing the highest disease burden. Tuberculosis (TB) burden is unevenly distributed across geographical regions and our…
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