CPDD: Adapting an autoregressive DNA language model for bidirectional phage genome modeling
Autoregressive DNA language models generate sequences ef[fi]ciently from left to right, but many genome-analysis and sequence-editing problems are naturally conditioned on both [fl]anks. We introduce CreatiPhage, a 144.5M-parameter autoregressive DNA language model for bacteriophages, and its diffusion extension, CreatiPhage Diffusion DNA-LM (CPDD). CPDD is a 147.5M-parameter bidirectional…
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