Competing routes back to firing shape population hyperexcitability and its selective suppression
Whether a neuron will fire again is fundamentally a different question from whether a quiescent neuron will activate. Even within the same neuron, successive spikes can follow distinct post-spike trajectories, with after-depolarization permitting early return to firing and depolarization block prolonging inactivity. Therefore, we propose that hyperexcitability involves changes in the…
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