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Genomic analysis of the Streptococcus anginosus group; taxonomic implications, evolutionary insights and clinical considerations

Background: The Streptococcus anginosus group (SAG) (S. anginosus, S. intermedius, and S. constellatus) causes serious, potentially life-threatening, invasive infections, often in otherwise healthy individuals. However, the group's diversity is still poorly understood, and with it, the ability to identify prognostic markers of severe disease. Methods: Long-read sequencing produced closed genomes…

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