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Provenance-aware handling of identical dengue genome records alters inferred envelope-protein variation in Bangladesh DENV-3

The reliability of interpreting dengue virus (DENV) envelope (E) protein variations depends on whether identical public sequence records are kept as representatives or eliminated based on provenance reviews. We evaluated three record-handling strategies using a frozen Bangladesh-associated dataset of 426 E sequences: exact-sequence deduplication, a prespecified provenance-sensitive exclusion…

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