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Long-read shotgun metagenomics identifies distinct urogenital microbial community states associated with functional potential and urinary tract infection during pregnancy

Urinary tract infections (UTIs) are among the most common bacterial infections during pregnancy and are associated with adverse maternal and neonatal outcomes. Although previous studies used enhanced culture, 16S rRNA gene sequencing, and/or short-read shotgun metagenomic sequencing to characterize the urogenital microbiome of adult females, few have assessed the urogenital microbiome during…

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