Hypoxemia is an Independent Risk Factor for Perioperative Thrombosis at High Altitude: A Retrospective Study of 11,084 Patients
Objective Perioperative thrombosis occurs at a significantly higher rate at high altitudes compared to low altitudes, severely threatening the safety of surgical patients. This study aims to determine the independent risk factors for perioperative thrombosis in high-altitude environments, providing a scientific basis for early clinical screening and targeted intervention. Methods Clinical data…
This retrospective study examines 11,084 surgical patients to determine independent risk factors for perioperative thrombosis at high altitudes. The research found that hypoxemia, defined as low arterial partial pressure of oxygen (PaO2), is an independent risk factor for postoperative thrombosis among patients undergoing surgery in high-altitude environments.
The study categorizes patients as either thrombosis or non-thrombosis based on the occurrence of postoperative thrombosis and collects various data points, including baseline characteristics, operative variables, and laboratory indicators. Univariate analysis and multivariate logistic regression are employed to identify significant risk factors, with the predictive performance of the model assessed using ROC curves, decision curve analysis, calibration plots, and nomograms.
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