Polygenic polymorphisms cooperate to drive expansion of HCMV adaptive NK cell and NK-like T cell populations
Human cytomegalovirus (HCMV) infection drives the expansion of several innate and innate-like lymphocyte populations. Characterized by high cell surface expression of NKG2C, these populations include the adaptive CD56+ Fc{epsilon}RI{gamma}- NK cell, an NK-like TCR{beta}+CD8+ T cell population and a V{gamma}9/V{delta}1+ T cells. Beyond NKG2C expression, both the adaptive NK cell and the NK-like T…
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