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Phage-Inducible Chromosomal Jumbo Islands (PICJIs) spreading antimicrobial resistance, host-adaptation factors and defense systems, a novel satellite family of nucleus-forming Chimalliviridae

Phage satellites are mobile genetic elements that depend on helper bacteriophages to promote their own dissemination. Here, we identified a novel family of large satellites, named Phage-Inducible Chromosomal Jumbo Islands (PICJIs), that are widespread in Escherichia coli and Salmonella enterica among diverse hosts, worldwide. These largest satellites to date (71.6 {+/-} 15.8 kbp) are specifically…

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