Mitochondria-Coupled Hitchhiking Drives Vimentin Intermediate Filament Transport

Vimentin intermediate filaments (VIFs) undergo active microtubule-dependent transport throughout the cell, with trajectories resembling those of motor-driven organelles, yet our recent work showed that only a small subset of VIFs lies close to microtubules. How VIFs engage the microtubule-based transport machinery, and whether additional transport routes contribute, remain unresolved. We…

biorxiv.org ·10h ago

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