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Microdroplet Generator Surrogate Enhancement and Inverse Design Through an Uncertainty-Guided Framework

Microfluidic droplet generation is critical for many applications, yet efficient device design in high-dimensional parameter spaces remains computationally prohibitive due to complex multiphase flow dynamics. This work presents a unified methodology that couples adaptive surrogate enhancement with simulation-driven inverse design. High-fidelity Volume-of-Fluid simulations provide ground-truth…

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