Decision benchmarking of cryo-EM re-refinement
Map fit is widely used in cryo-EM re-refinement. We benchmarked selection against retaining the deposited model (no operation), using packed-side-chain agreement with higher-resolution references. In a prespecified 3.0-3.6 [A] cohort (167 entries, 131 sequence groups), highest-correlation selection increased {chi}1 disagreement by 2.4{degrees} (95% interval 2.1-2.7{degrees}), with positive loss…
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