Yap is a key regulator of tracheoesophageal separation during foregut development
Separation of the anterior foregut into the esophagus and trachea involves dynamic cellular movement that requires the coordinated activity of multiple signaling pathways and transcription factors. Disruption of this process can result in esophageal atresia (EA) with or without tracheoesophageal fistula (TEF), manifesting in five major anatomical types (Types A-E). Here, we examine the role of…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
