VIGAT: VLM-guided gene activity quantification from single-cell ATAC-seq
Gene activity quantification from single-cell ATAC-seq is challenging because genomic regions informative of cell identity can vary across genes and tissues, while broadly accessible regions may provide limited cell-type-discriminative information. We developed VIGAT, a vision-language model (VLM)-guided tool that automates visual interpretation of ATAC coverage plots for adaptive gene…
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