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Fibronectin-Assisted Coating of Low-Molecular-Weight Fucoidan Creates a Biomimetic Interface for Endothelialization of Cobalt-Chromium Stents

Incomplete or delayed endothelialization after stent implantation compromises vascular healing and increases the risk of restenosis and late thrombosis. To address this limitation, Cobalt-Chromium (Co-Cr) stents were modified with a biomimetic coating combining Low-Molecular-Weight Fucoidan (LMWF), a sulfated polysaccharide with glycocalyx-mimetic properties, and fibronectin, to promote…

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