Extensive membrane lipid remodeling at the host-parasite interface of Toxoplasma gondii
Phosphoinositides regulate diverse membrane trafficking and signaling events in eukaryotic cells, yet their transbilayer distribution remains largely unexplored, particularly at host-parasite membrane interfaces. Here, we determined the membrane leaflet localization of phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) in Toxoplasma gondii…
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