Dual role of RBM3 in PEDV infection: stabilization of viral RNA and upregulation of the entry factor HSPA5
RBM3, a member of the cold-shock protein family, functions as an RNA chaperone that stabilizes target transcripts by binding to their untranslated regions (UTRs). Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus that poses a serious threat to the swine industry, and its replication heavily depends on its genomic and subgenomic RNAs, making these RNAs potential targets for host…
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