Class-wide sequence, structural, and docking-profile diversity of insect odorant receptors and structural specialization of Orco
Insect olfaction is facilitated by a heterotetrameric odorant receptor–odorant receptor co-receptor (OR-Orco) complex. However, extensive sequence divergence and lineage-specific expansion have complicated large-scale comparisons of OR repertoires across insects. Here, we integrated sequence similarity, structural similarity, and molecular docking to analyze ORs from 115 insect species. OR…
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