A cytotoxicity dataset for data-driven design of ionizable lipid nanoparticles
Ionizable lipid nanoparticles (LNPs) are widely used to deliver nucleic acid therapeutics, but the design of safe LNPs remains challenging due to the complex activity relationships among structure, composition, and physicochemical properties. Here, we present a curated dataset, the Lipid Nanoparticle Cytotoxicity Database (LNPCD), which aggregates 1,413 LNP cytotoxicity measurements across 1,288…
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