RNA assignment and segmentation geometry in Visium HD profiles of fibrostenotic Crohn's disease
Retrospective reuse of spatial transcriptomics often starts from a deposited bin-level Seurat object rather than the inputs needed to revisit upstream molecular processing. We tested whether image segmentation could support a defensible cell-like reconstruction under this constraint in two complete H&E-stained intestinal sections from a Visium HD study of Crohn's disease-associated fibrostenosis…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
