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Tissue-Derived Insoluble Type I and Type II Collagen Inks for 3D Printing of Fibrillar Collagen Scaffolds

Collagen is the primary structural component of the extracellular matrix, yet most printable collagen systems rely on soluble collagen, support baths, secondary polymers, or photochemical crosslinking. Here, we developed tissue derived insoluble type I and type II collagen inks for direct extrusion-based 3D printing without a sacrificial support bath. Type I collagen was isolated from bovine…

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