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Regionalisation of muscle nucleus heterogeneity in foetal skeletal muscle

Skeletal muscle is organized into functional domains with attachments at both extremities to tendons via the myotendinous junction (MTJ) and innervation in the middle via the neuromuscular junction (NMJ). In adult muscle, the molecular heterogeneity of muscle domains is described at the level of myonuclei with specialized MTJ and NMJ myonuclei at the tips and middle of muscle fibre. However, how…

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