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Polarization affects viscoelasticity and podosome distribution of primary human macrophages

Macrophages are essential cells of the innate immune system that regulate wound healing and tissue homeostasis. They exert diverse functions, depending on their polarization state, which can lead to either functional healing of the tissue or fibrosis. Macrophage polarization state is affected by both the local biochemical and mechanical microenvironment within the tissue, suggesting a possible…

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