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Inhibition of Hippo signalling disrupts germinative cell-cycle progression and larval development in Echinococcus multilocularis

The metacestode larval stage of Echinococcus multilocularis exhibits a remarkable capacity for sustained, infiltrative growth, driven by germinative cells, the parasite's only mitotically active cell population. Yet, despite this seemingly unlimited growth potential, cell proliferation and differentiation must remain tightly coordinated to maintain tissue organization and parasite development.…

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