Influenza H1N1 Imprinting Uncouples Serological and B-Cell Responses in Mice
Antigenic drift reduces the protective potential of antibodies generated against earlier influenza variants. Unfortunately, a new infection or vaccination often preferentially recalls antibodies targeting previously encountered strains, thereby limiting responses to newly emerged variants. Although this phenomenon, known as immunological imprinting, has been well documented at the serological…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
