How many mutations does it take to evolve a new function?
Biochemical and genetic networks in cells evolve to produce new functions. Evolution is guided by the genotype to phenotype map which describes how mutations at the molecular scale lead to changes in network function at the cellular scale. The number of genotypes is astronomically large which makes these maps very high dimensional. In this context, the simple question: How many mutations does it…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.