Generation of human iPSC-derived motor neurons with defined regional identities across the rostrocaudal axis
This study establishes a unified pipeline for generating human induced pluripotent stem cell (iPSC)-derived motor neurons (iMNs) with defined hindbrain, cervical, and lumbar identities to support anatomically resolved studies of motor neuron development and degeneration. Conventional differentiation methods can efficiently produce iMNs but provide limited control over rostrocaudal identity and…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
