Enhanced Antimicrobial Potency and Therapeutic Index of a Defined C12 Quaternary Ammonium Compound
Skin and soft tissue infections (SSTIs) remain a major clinical burden and are complicated by antimicrobial resistance, polymicrobial infections, and biofilm-mediated therapeutic tolerance. Topical antimicrobials can provide localized activity while reducing systemic exposure, but currently available agents are limited by narrow spectra, cytotoxicity, poor antibiofilm activity, and resistance…
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