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Collagen4 fluorescent protein knock-in lines reveal remodeling of cardiovascular basement membranes

Basement membranes (BMs) are specialized extracellular matrix structures that provide structural support and regulate cellular behavior. Although BM composition and organization are dynamically remodeled during development and tissue regeneration, the remodeling of individual BM components in the cardiovascular system (CVS) remain incompletely characterized. Here, we focused on Collagen4 (Col4),…

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