Transcriptomic similarity guides source selection beyond tissue lineage
Perturbational and pharmacogenomic maps remain incomplete across cellular contexts, leaving a practical source-selection question before response prediction: which measured context should inform an unmeasured target? We tested whether baseline transcriptomic similarity ranks candidate sources for held-out targets, separating source ranking from aggregation and transfer-uncertainty decisions.…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
