Scooby-2: fine-tuning AlphaGenome for single-cell genomic track prediction
Sequence-to-function models predict genomic tracks from DNA sequence. AlphaGenome has been shown to outperform previous models, including Borzoi, on most track-prediction and variant-effect benchmarks. However, like its predecessors, it predicts tracks only for predefined, mostly bulk-derived cell types and tissues. While Scooby has extended Borzoi to single-cell resolution, a single-cell…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
