Quantifying the role of hyaluronic acid on collagen fiber mechanics via femtosecond laser ablation
Despite therapeutic use of hyaluronic acid (HA) for tendon injuries and tendinopathies, the role of HA in tendon mechanical behavior remains poorly understood. Here, we describe the development of a method that integrates femtosecond laser ablation, second harmonic generation imaging, and mechanical testing to quantify collagen fiber recoil within intact murine tendons under load. Fiber recoil…
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