An Integrated Miniaturized Metabologenomics Workflow for High-Throughput Actinomycetes Prioritization
Antibiotic resistance is a growing global health threat, while the discovery of new antimicrobial agents remains constrained by labor-intensive cultivation, extraction, and screening workflows. We developed a miniaturized, high-throughput metabologenomics workflow integrating Duetz system-based microfermentation, extraction-free UHPLC-HRMS/MS profiling, antibacterial screening, and genome mining.…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
