A High-Sensitivity and High-Throughput LC-MS Workflow for Low-Input and Single-Cell Proteomics
Single-cell proteomics (SCP) requires sample preparation that minimizes sample loss and highly sensitive LC-MS analysis because the amount of protein available from a single cell is extremely limited. Here, we developed an integrated workflow for low-input and single-cell proteomics based on single-cell proteomics by LMNG-assisted sample preparation (scpLASP), which enables microliter-scale…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
