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Siderophore-Mediated Competition Between Cystic Fibrosis Pathogens Increases Virulence Factor Production

The airways of people with cystic fibrosis (CF) are colonized by a polymicrobial community and coinfections with multiple pathogens may exacerbate disease. By analyzing 16S rRNA gene sequencing datasets, we determined that Achromobacter-Pseudomonas coinfection was associated with worse lung function than infection with either pathogen alone, or coinfections with Pseudomonas and other CF bacterial…

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