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Predictive consequences of alternative representations of metabolic measurements: A controlled synthetic study of categories, longitudinal information and transition preservation

Metabolic categories summarise observed abnormalities, but shared labels may conceal distinctions relevant to future evolution. We examined the predictive consequences of alternative representations under controlled synthetic dynamics. For each of six generating scenarios, twenty independent confirmation cohorts contained 5,115 simulated individuals each, including 1,023 held out. Observations…

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