Flotillin acts as a regulatory cellular barrier against invasion by Escherichia coli K1
Pathogenic microorganisms that cause neonatal meningitis must cross the blood-brain barrier to reach the central nervous system. Escherichia coli K1 remains a leading pathogen in cases of neonatal bacterial meningitis and invades the endothelium in the brain microvasculature. Signalling through a cascade of sphingosine kinase activity and the epidermal growth factor receptor (EGFR) has been…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
